Overview
Tesamorelin is a synthetic analog of growth hormone–releasing hormone (GHRH). It stimulates the pituitary gland to increase endogenous growth hormone secretion, which subsequently raises insulin-like growth factor 1 (IGF-1) levels.

Cellular Longevity +2
Tesamorelin — GHRH analog for visceral fat and IGF-1 research.
Tesamorelin is a stabilized 44-amino-acid GHRH analog, FDA-approved for HIV-associated lipodystrophy. It stimulates pulsatile endogenous GH release without bypassing pituitary feedback.
Each PeptidePen is filled in a controlled cleanroom and sealed with tamper-evident packaging. Batch documentation includes identity confirmation, HPLC purity analysis and concentration verification. Strictly for in-vitro research — not for human or veterinary use.
A full breakdown of mechanism, clinical findings, dosing references and safety signals — for researchers who want the complete picture.
Tesamorelin is a synthetic analog of growth hormone–releasing hormone (GHRH). It stimulates the pituitary gland to increase endogenous growth hormone secretion, which subsequently raises insulin-like growth factor 1 (IGF-1) levels.
Unlike direct growth hormone administration, Tesamorelin works through physiological stimulation of the GH axis, preserving normal pulsatile secretion. It is clinically recognized for reducing visceral adipose tissue and improving metabolic markers. It has been widely studied in patients with abdominal fat accumulation and metabolic disturbances.
By enhancing natural GH production, Tesamorelin supports fat metabolism, lean body mass preservation, and cellular repair processes.
• Reduces visceral abdominal fat
• Supports lean muscle mass maintenance
• Enhances metabolic function
• Improves lipid profile parameters
• Supports cellular regeneration
• May improve liver fat markers
• Contributes to better body composition
• Supports healthy IGF-1 regulation
• May enhance recovery capacity
• Supports overall metabolic resilience
Tesamorelin has been evaluated in randomized clinical trials for reduction of visceral adipose tissue. Studies demonstrated significant decreases in abdominal fat and improvements in lipid profiles and inflammatory markers.
Research confirms that Tesamorelin increases endogenous growth hormone and IGF-1 within physiological ranges. Clinical investigations also showed improvements in body composition and metabolic health parameters.
• Recommended dose: 1 mg daily in the evening, before bedtime and 1–2 hours after meals
• Correct dose in units: 20 units per day
• Frequency & course duration: Once daily for 2–6 weeks
• Pause: 1 month break after cycle
Unit conversion
One pen contains 200 units /2 ml:
• 1 unit = 0.05 mg (50 mcg)
• 20 units = 1 mg
One Tesamorelin pen lasts approximately 10 days.
If following the label cycle (2–6 weeks), you would need:
• 2-week cycle → 2 pens
• 4-week cycle → 3 pens
• 6-week cycle → 5 pens
Apply to abdominal area or front thigh. Rotate application sites. Hold the device in place for 10 seconds before removal.
Peptides Commonly Combined with Tesamorelin:
• Ipamorelin – synergistic GH stimulation
• CJC-1295 No DAC – enhanced GH pulsatility
• HGH Frag 176-191 – targeted fat metabolism
• MOTS-C – metabolic optimisation support
• Mild injection site irritation
• Temporary water retention
• Headache
• Mild flushing
These effects are typically dose-dependent and reversible.
This compound is intended strictly for personal observation and research-related purposes. The information presented is based on scientific literature and is not intended to diagnose, treat, or prevent any medical conditions.
Significant reduction in visceral adipose tissue
Raises IGF-1 within physiologic ranges
Improves lipid panel and cognition in aging studies
Preserves pulsatile GH architecture
Research dosing: 1–2 mg SC nightly, 5 on / 2 off cycles.
For in-vitro research design reference only.
Form
Pre-mixed pen
Purity
≥99% HPLC
Storage
2–8°C
Shipping
Cold-chain
COA
Batch-matched
Select pen size and shipping region at checkout.
Each batch is HPLC-assayed and documented.
Insulated, temperature-logged delivery.
Reference dosing and references included.
Common questions about Tesamorelin and PeptidePen orders.
No. All PeptidePen products are strictly for in-vitro laboratory research. Not intended for human or veterinary use.
Each pen ships with a batch-matched certificate of analysis. A digital copy is also available on request via your order confirmation.
Orders ship cold-chain (2–8°C) with insulated packaging, ice packs and a temperature log. Tracked delivery in the US and EU.
Yes. Contact our team for institutional pricing, custom concentrations and recurring shipments.
Damaged or off-spec pens are replaced free of charge. Contact support within 7 days of delivery.
Pre-mixed, batch-assayed, cold-chain shipped — order before 2pm for same-day dispatch.