Cellular Longevity +2
SS-31 (Elamipretide) — cardiolipin-binding mitochondrial peptide.
SS-31 / Elamipretide is a tetrapeptide that selectively binds cardiolipin on the inner mitochondrial membrane, stabilizing cristae architecture and improving electron-transport efficiency. Studied for heart failure, sarcopenia and age-related mitochondrial decline.
Each PeptidePen is filled in a controlled cleanroom and sealed with tamper-evident packaging. Batch documentation includes identity confirmation, HPLC purity analysis and concentration verification. Strictly for in-vitro research — not for human or veterinary use.
A full breakdown of mechanism, clinical findings, dosing references and safety signals — for researchers who want the complete picture.
SS-31, also known as Elamipretide, is a mitochondria-targeted peptide designed to bind cardiolipin within the inner mitochondrial membrane. By stabilising mitochondrial structure and improving electron transport chain efficiency, SS-31 enhances ATP production and reduces oxidative stress.
SS-31 acts directly at the mitochondrial level, supporting cellular energy production and reducing reactive oxygen species formation.
It is studied in ageing, cardiovascular dysfunction, neurodegenerative conditions, and metabolic diseases.
• Supports mitochondrial energy production
• Reduces oxidative stress
• Improves cellular ATP output
• Supports cardiovascular function
• May enhance muscle endurance
• Supports brain mitochondrial health
• Promotes cellular resilience
• Supports recovery from metabolic stress
• May improve exercise tolerance
• Contributes to healthy aging processes
SS-31 has been evaluated in multiple clinical and translational studies targeting mitochondrial dysfunction. Research demonstrates improved mitochondrial bioenergetics and reduced oxidative damage.
Studies in cardiovascular and skeletal muscle models show improved mitochondrial efficiency and cellular performance. Human trials suggest improved mitochondrial function markers without major adverse effects.
Dosage and Administration of SS-31 (10 mg / 2 ml):
• Recommended dose: 2.5 mg daily
• Correct dose in units: 50 units daily
• Frequency & course duration: Daily for 2–4 weeks
• Pause: 4 weeks break
• 1 unit = 0.05 mg (50 mcg)
• 50 units = 2.5 mg
One SS-31 pen lasts approximately 4 days.
For a 2–4 week cycle:
• 2 weeks (14 days) → 4 pens
• 4 weeks (28 days) → 7 pens
Apply to recommended area. Rotate application sites. Hold the device in place for 10 seconds before removal.
Peptides Commonly Combined with SS-31
• MOTS-C – mitochondrial metabolic support
• BPC-157 – tissue repair synergy
• NAD+ precursors – cellular energy enhancement
• GHK-Cu – regenerative support
• Mild injection site discomfort
• Temporary fatigue during adaptation phase
• Mild headache
Generally well tolerated in studied doses.
This compound is intended strictly for research and observation purposes only. The information provided is not medical advice and is not intended to diagnose or treat any condition.
Restores mitochondrial cristae and ATP output
Reduces ROS leak from Complex I/III
Improves exercise capacity in aged models
Supports cardiac and renal mitochondrial health
Binds cardiolipin without altering membrane potential, preserving ETC supercomplex assembly.
Form
Pre-mixed pen
Purity
≥99% HPLC
Storage
2–8°C
Shipping
Cold-chain
COA
Batch-matched
Select pen size and shipping region at checkout.
Each batch is HPLC-assayed and documented.
Insulated, temperature-logged delivery.
Reference dosing and references included.
Common questions about SS-31 (Elamipretide) and PeptidePen orders.
No. All PeptidePen products are strictly for in-vitro laboratory research. Not intended for human or veterinary use.
Each pen ships with a batch-matched certificate of analysis. A digital copy is also available on request via your order confirmation.
Orders ship cold-chain (2–8°C) with insulated packaging, ice packs and a temperature log. Tracked delivery in the US and EU.
Yes. Contact our team for institutional pricing, custom concentrations and recurring shipments.
Damaged or off-spec pens are replaced free of charge. Contact support within 7 days of delivery.
Pre-mixed, batch-assayed, cold-chain shipped — order before 2pm for same-day dispatch.
