Overview
Kisspeptin-10 is a biologically active fragment of the Kisspeptin peptide family. It plays a crucial role in regulating the hypothalamic–pituitary–gonadal (HPG) axis by stimulating gonadotropin-releasing hormone (GnRH) secretion.

Hormonal & Reproductive
Kisspeptin-10 — upstream regulator of the HPG axis.
Kisspeptin-10 is the active decapeptide of the KISS1 gene product, the master initiator of GnRH pulsatility. Studied for hypogonadism, fertility, and post-cycle endocrine recovery.
Each PeptidePen is filled in a controlled cleanroom and sealed with tamper-evident packaging. Batch documentation includes identity confirmation, HPLC purity analysis and concentration verification. Strictly for in-vitro research — not for human or veterinary use.
A full breakdown of mechanism, clinical findings, dosing references and safety signals — for researchers who want the complete picture.
Kisspeptin-10 is a biologically active fragment of the Kisspeptin peptide family. It plays a crucial role in regulating the hypothalamic–pituitary–gonadal (HPG) axis by stimulating gonadotropin-releasing hormone (GnRH) secretion.
Through activation of GnRH neurons, Kisspeptin increases luteinizing hormone (LH) and follicle-stimulating hormone (FSH), supporting reproductive hormone balance.
It is studied for fertility optimisation, hormonal regulation, and neuroendocrine function.
• Supports natural testosterone production
• Stimulates LH and FSH secretion
• Regulates reproductive hormone axis
• Supports fertility protocols
• Enhances hormonal signaling balance
• May improve libido
• Supports ovarian and testicular function
• Contributes to endocrine regulation
• Supports hypothalamic signaling pathways
• Promotes hormonal homeostasis
Clinical studies show that Kisspeptin administration significantly increases LH secretion in both men and women. Research confirms its role as a key upstream regulator of reproductive hormones.
Investigations in fertility medicine demonstrate controlled stimulation of the HPG axis with favorable safety profiles.
Dosage and Administration of Kisspeptin-10 (5 mg / 2 ml)
One pen contains 200 units per 2 ml:
• Recommended dose: 200mcg daily in the morning on an empty stomach
• Correct dose in units: 8 units daily
• Frequency & course duration: Daily for 4–8 weeks
• Pause: 4 weeks break
• 1 unit = 0.025 mg (25 mcg)
• 4 units = 100 mcg
• 8 units = 200 mcg
• 10 units = 250 mcg
One Kisspeptin pen lasts approximately 25 days.
How many pens are needed per cycle?
• 4 weeks (28 days) → 2 pens
• 6 weeks (42 days) → 2 pens
• 8 weeks (56 days) → 3 pens
Apply to abdominal area or the front thigh. Rotate application sites regularly. Hold pen in place for 10 seconds before removal.
• Temporary flushing
• Mild headache
• Nausea
• Hormonal fluctuations if overdosed
Generally well tolerated when used within physiological microgram ranges.
This compound is intended strictly for personal observation and research-related purposes. The information presented is based on scientific literature and is not intended to diagnose, treat, or prevent any medical conditions.
Stimulates endogenous LH and FSH release
Restores GnRH pulsatility
Supports natural testosterone and estradiol
Studied in fertility and hypothalamic amenorrhea
Form
Pre-mixed pen
Purity
≥99% HPLC
Storage
2–8°C
Shipping
Cold-chain
COA
Batch-matched
Select pen size and shipping region at checkout.
Each batch is HPLC-assayed and documented.
Insulated, temperature-logged delivery.
Reference dosing and references included.
Common questions about Kisspeptin and PeptidePen orders.
No. All PeptidePen products are strictly for in-vitro laboratory research. Not intended for human or veterinary use.
Each pen ships with a batch-matched certificate of analysis. A digital copy is also available on request via your order confirmation.
Orders ship cold-chain (2–8°C) with insulated packaging, ice packs and a temperature log. Tracked delivery in the US and EU.
Yes. Contact our team for institutional pricing, custom concentrations and recurring shipments.
Damaged or off-spec pens are replaced free of charge. Contact support within 7 days of delivery.
Pre-mixed, batch-assayed, cold-chain shipped — order before 2pm for same-day dispatch.